BOSCH PHARMACEUTICALS (PVT) LTD
Vinjec Injection 500Mg 1 Vial
Vinjec Injection 500Mg 1 Vial
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SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Vancomycin HCI
Used For
Bacterial Infection
How it works
The bactericidal action of Vancomycin results primarily from inhibition of cell-wall biosynthesis. In addition, Vancomycin alters bacterial-cell membrane permeability and RNA synthesis. There is no cross-resistance between Vancomycin and other antibiotics.
USAGE AND SAFETY
Dosage
Vancomycin HCI
Side Effects
Infusion related events , nephrotoxicity , ototoxicity , neutropenia , nausea , chills , fever , rashes , eosinophillia , phlebitis , decreased BP , dyspnoea , stridor , pruritis , mucosal inflammation , severe pain at inj site.
Drug Interactions
Neurotoxic , ototoxic or nephrotoxic drugs , anesthetics , PPIs , antimotility agents.
Indication
Serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci, pencillin-alergic patients. For infections caused by vancomycin susceptible organisms for initial therapy, when methicillin resistant staphylococci are suspected. In the treatment of staphylococcal endocarditis, infections due to staphylococci, including septicemia, bone infections, lower respiratory tract infections, and skin & skin structure infections.
When not to Use
Vancomycin HCI is contraindicated in patients with known hypersensitivity to this antibiotic.
PRECAUTIONS
Precaution
In order to minimise the risk of nephrotoxicity when treating patients with underlying renal dysfunction or patients receiving concomitant therapy with an aminoglycoside. Serial monitoring or renal function should be performed and particular care should be taken in following appropriate dosing schedules.
WARNINGS
Warning 1
Rapid bolus administration (e.g. Over several minutes) may be associated with exaggerated hypotension and rarelycardiac a rest.
Warning 2
Vancomycin HCI should be administered in a diluted solution over a period of not less than 60 minutes to avoid rapid-infusion-related reactions. Stopping the infusion usually results in prompt cessation of there reactions.
Warning 3
Ototoxicity has occurred in patients receiving Vancomycin HCI. It may be transient or permanent. It has been reported mostly in patients who have given excessive doses. who have an underfying hearing loss, or who are receiving concomitant therapy with another ototoxic agent,such as an aminoglycoside .
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.