SANOFI AVENTIS
Targocid Injection 400 Mg 1 Amp
Targocid Injection 400 Mg 1 Amp
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SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Teicoplanin
Used For
Bacterial Infection
How it works
Teicoplanin inhibits the growth of susceptible organisms by interfering with cell-wall biosynthesis at a site different from that affected by beta-lactams. Peptidoglycan synthesis is blocked by specific binding to D-alanyl-D-alanine residues.
USAGE AND SAFETY
Dosage
Teicoplanin
Side Effects
Common (may affect up to 1 in 10 people) : • Rash, erythema, pruritus • Pain • FeverUncommon (may affect up to 1 in 100 people) : • decrease in platelet count. • raised blood levels of liver enzymes • raised in blood levels of creatinine (tomonitor your kidney) • hearing loss, ringing in the ears or a feeling that you, or things around you are moving • feeling or being sick (vomiting), diarrhoea • feeling dizzy or headacheRare (may affect up to 1 in 1,000 people) : • infection (abscess). Not known (frequency cannot be estimated from the available data) : • problems where the injection was given - such as reddening of the skin, pain or swelling
Drug Interactions
Aminoglycosides, colistin, amphotericin B, ciclosporin, cisplatin, furosemide, and ethacrynic acid .
Indication
It is used in adults and children (including newborn babies) to treat bacterial infections of:- The skin and underneath the skin - sometimes called ‘soft tissue’- The bones and joints- The lung- The urinary tract- The heart - sometimes called ‘endocarditis’- The abdominal wall - peritonitis- The blood, when caused by any of the conditions listed above.
When not to Use
Do not use Teicoplanin if you are allergic to teicoplanin or any of the other ingredients of this medicine.
PRECAUTIONS
Precaution
Serious, life-threatening hypersensitivity reactions, sometimes fatal, have been reported with teicoplanin (e.g. anaphylactic shock). If an allergic reaction to teicoplanin occurs, treatment should be discontinued immediately and appropriate emergency measures should be initiated.
WARNINGS
Warning 1
In rare cases (even at the first dose), red man syndrome (a complex of symptoms including pruritus, urticaria, erythema, angioneurotic oedema, tachycardia, hypotension, dyspnoea) has been observed. Stopping or slowing the infusion may result in cessation of these reactions. Infusion related reactions can be limited if the daily dose is not given via bolus injection but infused over a 30-minute period.
Warning 2
Life-threatening or even fatal cutaneous reactions Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) have been reported with the use of teicoplanin. If symptoms or signs of SJS or TEN (e.g. progressive skin rash often with blisters or mucosal lesions) are present teicoplanin treatment should be discontinued immediately.
Warning 3
The rational use of teicoplanin should take into account the bacterial spectrum of activity, the safety profile and the suitability of standard antibacterial therapy to treat the individual patient. On this basis it is expected that in most instances teicoplanin will be used to treat severe infections in patients for whom standard antibacterial activity is considered to be unsuitable.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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