Roche Pakistan Limited
Ristova Inj 100mg 2vialx10ml
Ristova Inj 100mg 2vialx10ml
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INTRODUCTION
RISTOVA 100MG INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to treat blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to treat various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals).
It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RISTOVA 100MG INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion).
Before receiving RISTOVA 100MG INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution.
RISTOVA 100MG INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RISTOVA 100MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RISTOVA 100MG INJECTION.
The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens.
USES OF RISTOVA 100MG INJECTION
It is used to treat:
- Blood cancer (Chronic lymphocytic leukaemia)
- Lymph cancer (Non-Hodgkin’s Lymphoma)
- Rheumatoid arthritis (joint pain and inflammation)
- Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels)
- Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals)
HOW RISTOVA 100MG INJECTION WORKS
RISTOVA 100MG INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in treating various autoimmune diseases.
DIRECTIONS FOR USE
RISTOVA 100MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously).
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF RISTOVA 100MG INJECTION
COMMON
- Increased infections (bacterial, viral or fungal)
- Low RBC, WBC and platelet counts in blood
- Nausea, vomiting, diarrhea, stomach pain, constipation, indigestion
- Mouth ulcers
- Hair loss
- Fever, chills, pneumonia, shingles, cold, sinusitis
- Thrush, urinary tract infection
- Headache, dizziness, tiredness, weakness
- Hepatitis B infection
- High blood sugar and cholesterol levels
- Weight loss, lack of appetite
- Numbness, tingling, pricking, burning sensation on the skin
- Restlessness, problems in falling asleep, anxiety, depression
- Flushing (skin redness)
- Eye inflammation or watery eyes
- Ringing sound in the ears, ear pain
- Uneven or fast heart rate, high or low blood pressure
- Shortness of breath, runny nose, nasal itching and repeated sneezing
- Increased sweating, night sweats
- Muscle pain, joint pain, back pain, neck pain
- Pain while passing urine
- Fungal foot infection (athlete’s foot)
- Tremors (shakiness)
- Swelling of the hands or ankles
UNCOMMON
- Blood clotting problems
- Changes in taste
- Slow heart rate
- Chest tightness and lung problems
RARE
Contact your doctor immediately if you experience any of the following side effects:
- Fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain
- Fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell
- Signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems)
- Signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever.
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