Chiesi Pharmaceuticals (Pvt) Ltd
Clenil Inhaler 250Mcg
Clenil Inhaler 250Mcg
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SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Beclomethasone dipropionate
Used For
Asthma
How it works
Beclomethasone dipropionate is a pro-drug with weak glucocorticoid receptor binding affinity. It is extensively hydrolyzed via esterase enzymes to the active metabolite Beclomethasone-17-monopropionate (B-17-MP), which has high topical anti-inflammatory activity.
USAGE AND SAFETY
Dosage
Beclomethasone dipropionate
Side Effects
Candidiasis of the throat and mouth may develop in some patients but this can be treated without discontinuation of Beclomethasone therapy. - Hoarseness or throat irritation may also occur. - As with other inhaled therapy, paradoxical bronchospasm with wheezing may occur immediately after dosing. Immediate treatment with an inhaled fast-acting bronchodilator is required. Beclomethasone dipropionate should be discontinued immediately and alternative prophylactic therapy introduced. - Systemic effects of inhaled corticosteroids may occur particularly at high doses prescribed for prolonged periods. These may include adrenal suppression, growth retardation in children and adolescents, decrease in bone mineral density, cataract and glaucoma. - Hypersensitivity reactions including rashes, urticaria, pruritus and erythema and edema of the eye, face, lips and throat (angioedema) have been reported. - Psychiatric disorders including psychomotor hyperactivity, sleep disorders, anxiety, depression, aggression and behavioral changes (predominantly in children).
Drug Interactions
Ethanol , disulfiram or metronidazole.
Indication
Beclomethasone dipropionate is indicated in the prophylactic management of mild, moderate, or severe asthma in adults or children.
When not to Use
Beclomethasone dipropionate is contraindicated in: - Patients with a history of hypersensitivity to the drug or any component of the product. - Tubercular (active or quiescent) and local viral infections.
PRECAUTIONS
Precaution
Patients should be properly instructed on the use of the inhaler and their technique checked. They should also be made aware that Beclomethasone dipropionate inhaler has to be used regularly, even when they are asymptomatic, for optimum benefit.
WARNINGS
Warning 1
Lack of response or severe exacerbations of asthma should be treated by increasing the dose of inhaled Beclomethasone dipropionate and if necessary, by giving a systemic steroid and/or an antibiotic if there is an infection, together with ß-agonist therapy .
Warning 2
Special care is necessary for the first months after the transfer until the hypothalamic-pituitary-adrenal (HPA) system has sufficiently recovered to enable the patient to cope with emergencies such as trauma, surgery or infections.
Warning 3
In some patients inhaled Beclomethasone dipropionate may cause hoarseness or throat irritation. It may be helpful to rinse the mouth out with water immediately after inhalation. The use of a spacer device may be considered.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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