UNIMARK PHARMACEUTICALS
Carsel Plus 50Mg
Carsel Plus 50Mg
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SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Metoprolol Tartarate , Hydrochlorothiazide
Used For
Hypertension
How it works
Metoprolol is a beta-adrenergic blocking agent which blocks the agonistic effect of the sympathetic neurotransmitters by competing for receptor binding sites. Cardioselective beta-blockers block beta-l receptors in the heart at low doses and only begin to block beta-2 receptors at increased doses, Metoprolol crosses the blood-brain barrier and placenta, and is excreted in breast milk. Hydrochlorothiazide acts on the distal convoluted tubules and inhibits the sodium chloride co-transporter system. This action leads to a diuretic action that lowers blood pressure, but there is also a potassium loss in the urine.
USAGE AND SAFETY
Dosage
Metoprolol Tartarate , Hydrochlorothiazide
Side Effects
Allergic reaction, bradycardia, breathing difficulty and chest pain, confusion, congestive heart /failure, hallucination, hepatotoxicity, leukopenia, mental depression. psoriasiform eruption, slow irregular heart beat, reduced peripheral circulation, thrombocytopenia, withdrawal reactions, dizziness or faint, nausea, vomiting, diarrhoea and abdominal discomfort, fatigue, headache, paresthesia, insomnia, decreased sexual ability, disturbance of vision, trembling and sweating.
Drug Interactions
Antidiabetic Agents, Oral, or insulin , Calcium Channel Blocking Agent, Clonidine, Diazoxide, Guanabenz Antihypotensive , Cocaine , Monoamine Oxidase (MAO) inhibitors, including Furazolidone, Pargyline,Procarbazine and Sympathomimetics .
Indication
This medication is indicated for the treatment of Angina pectoris , Hypertension , Cardiac arrhythmias , Myocardial infarction , Migraine prophylaxis . This medication is also used as an adjunct in the treatment ofHyperthyroidism , Early management of acute myocardial infarction .
When not to Use
Known hypersensitivity to metoprolol or when the following medical problems exist: Atrioventricular block of 2nd or 3rd degree , Sinus bradycardia , Cardiac failure , Severe peripheral arterial circulatory disorderHypotension , Cardiogenic shock .
PRECAUTIONS
Precaution
Abrupt cessation of therapy with a beta-blocker should be avoided where possible, it should be withdrawn gradually over a period of I0 days. During its withdrawn, the patients should be kept under close surveillance.
WARNINGS
Warning 1
Metoprolol may aggravate bradycardia symptoms of peripheral arterial circulatory disorders and anaphylactic shock.
Warning 2
In patients with phaeochromocytoma, an alpha-blocker should be given concomitantly.
Warning 3
In patients with significant hepatic dysfunction, it may be necessary to adjust the dosage because metoprolol undergoes biotransformation in the liver.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.